Dr. Rajendran and his wife, Mrs. Sasikala Rajendran, have shared the responsibility of raising their son and daughter with strong social values and a deep respect for their cultural heritage. These values are clearly reflected in their children's impeccable careers as promising doctors dedicated to humane service.

Their son, Dr. R. Sudhir venkatesh is currently pursuing a super-specialty degree in clinical Haematology at Believers Church Medical College Hospital in Thiruvalla, Kerala. He is married to Dr. P. Nivedha, M.D., who works as a Consultant Psychiatrist at Kumaran Hospital in Chennai. They’re blessed with a boy Master. Vihaan venkatesh S.N

Their daughter, Dr. R. Kavi Sowmya, is a Consultant in Obstetrics and Gynaecology at NAAM Hospital in Salem. She is married to Dr. S. Aravind, who serves as a Consultant in Radiodiagnosis at the same hospital. They’re blessed with a boy Master. Krishna S Aravind.